Bisci produces wines from Marche, a region in central Italy known for white varieties of mineral precision and structure. The winery's focus centers on Verdicchio, the region's signature grape—a variety prized for its acidity, salinity, and aging potential. Verdicchio di Matelica Senex Riserva and Verdicchio di Matelica Vigneto Fogliano represent the winery's expression of this varietal, each rated by major critics including Wine Advocate, Wine Spectator, Decanter, Wine Enthusiast, and Falstaff. The portfolio also includes Villa Castiglioni Marche Rosso, a blend of Merlot and Sangiovese that reflects the region's capacity for structured red wines. Bisci's wines demonstrate the character of Marche's terroir: whites of tension and minerality, reds of balance and depth.