Cusumano operates in Terre Siciliane, the expansive wine region of southern Sicily. The winery's portfolio centers on Nerello Mascalese from Etna, the volcanic terrain that defines northeastern Sicily's most prestigious reds. Alta Mora Tyme Etna Rosso and Alta Mora Guardiola Etna Rosso showcase the variety's mineral precision and structural depth—wines that have drawn assessment from Wine Enthusiast, Wine Spectator, Wine Advocate, Falstaff, and Decanter. The winery also produces Moscato dello Zucco, a white that demonstrates the aromatic potential of Moscato in this terroir. Etna's high altitude and volcanic soils yield wines of distinctive character: Nerello Mascalese develops savory complexity and fine tannins, while Moscato expresses floral and stone-fruit notes. Cusumano's focus on these indigenous varieties reflects the broader identity of Sicilian viticulture—a region where ancient grape traditions meet modern winemaking.