Annona works with Montepulciano, the dark-skinned grape that defines red winemaking across Central Italy's Abruzzo region. The winery's portfolio centers on expressions of this variety: Modo Antico Montepulciano d'Abruzzo, a structured interpretation that has drawn attention from Wine Enthusiast and Wine Spectator; alongside Cerasuolo d'Abruzzo, the region's signature rosé made from the same grape, and a core Montepulciano d'Abruzzo. Montepulciano thrives in Abruzzo's continental climate and limestone-rich soils, yielding wines with dark fruit character, moderate tannins, and the mineral backbone that reflects the terroir. Annona's focus on single-varietal expressions allows the grape's range to emerge across different styles—from the dry rosé to the age-worthy reds that anchor the range.