Hesketh produces wines from South Australia that have drawn attention from major critics including Wine Spectator, Decanter, Wine Advocate, and Wine Enthusiast. The winery's portfolio centers on Shiraz and Cabernet Sauvignon blends, alongside Chardonnay. The Cabernet Sauvignon–Shiraz blend represents the winery's highest-rated offering, followed by the Lobethal Chardonnay and The Protagonist Shiraz. These wines reflect South Australia's capacity for ripe, structured reds and compelling white varietals, anchored in the region's warm climate and established vineyard sites.